Sense of smell reduction as factor for mammoth’s and other mammals extinction. Immunoglobulins as possible markers

One of the possible mechanisms for the extinction of animals during climate change could be a violation of the sense of smell due to the development of allergies when the flora changes. During the breeding season, susceptibility to odors is very important for animals. The development of allergies from plant pollen, changes in pollen's allergic toxicity, pollen's release period increasing or the emergence of a large quantity of flowering plants during climate change, could lead to decrements in sensitivity to odors in animals during the breeding season. This may explain the extinction of animals due to a decrease in sexual intercourse. Probably these changes in allergic responses of mammoths at period of climate changes led to a decrease in the mammoth population and, as a result, to their disappearance. For example, elephants have the most sensitive sense of smell. Immunoglobulin’s traces can provide information about the health of extinct animals. The search and characterization of immunoglobulins from extinct animals and comparison with the plant composition (pollen, plant remains) found with the animals can provide information about possible allergic diseases of these animals. The purpose of our article is to show that immunoglubulin’s fragments found in the remains of mammoths indicate the presence of possible allergic diseases in mammoths. Also, the purpose of this work is to propose a new evolutionary mechanism for the extinction of mammoths and other animals based on the disruption of communications between animals during the breeding season due to a decrease in the sense of smell and sensitivity to odors due to allergies to plants. • Discovery of immunoglobulins in permafrost paleontology samples. • Allergens (plant’s metabolites, volatile organic compounds, pollen) induced sex contact inhibition as one of factor animals extinction. • Disruption of chemical signaling between animals as a factor in animal extinction. The influence of plants and parasites on signaling disruption between animals.