Irradiation alters extracellular vesicle microRNA load in the serum of patients with leukaemia

20242 citationsJournal Articlehybrid Open Access

Authors

Stephanie Hehlgans · Goethe University Frankfurt

Denise Eckert · German Cancer Research Center

Daniel Martín · Goethe University Frankfurt

Katalin Lumniczky · Frédéric Joliot-Curie National Research Institute for Radiobiology and Radiohygiene

Gesine Bug · Goethe University Frankfurt

Claus Rödel · Goethe University Frankfurt

Franz Rödel

Abstract

As compared to healthy controls and following irradiation, we have identified differentially regulated miRNAs in serum-derived EVs from patients with leukaemia that may serve as possible biomarkers of leukaemic disease and treatment and radiation exposure.

Topics & Keywords

Extracellular vesicles in disease MicroRNA in disease regulation Circular RNAs in diseases

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Strahlentherapie und Onkologie

Volume 201, Issue 2, pp. 173-184

DOI: 10.1007/s00066-024-02307-6

Field-Weighted Citation Impact: 0.46