Fecal Immunochemical Test Positivity Thresholds: An International Survey of Population-Based Screening Programs

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Authors

Graeme P. Young · Flinders University

Sally C. Benton · Bowel Cancer UK

Robert S. Bresalier · The University of Texas MD Anderson Cancer Center

Han‐Mo Chiu · National Taiwan University

Evelien Dekker · Amsterdam University Medical Centers

Callum G. Fraser · University of Dundee

Marieke A. M. Frasa

Abstract

This international survey has documented the wide range of FIT positivity thresholds that are in current use. Quantitative FITs enable programs to achieve the desired program outcomes within available resource constraints by adjusting the positivity threshold. This supports the need for enabling positivity threshold adjustment of emerging new screening tests based on novel predictive biomarkers, rather than providing inflexible test endpoints.

Topics & Keywords

Colorectal Cancer Screening and Detection Gastric Cancer Management and Outcomes Gastrointestinal disorders and treatments

Publication Details

Published in: Digestive Diseases and Sciences

Volume 70, Issue 5, pp. 1637-1645

DOI: 10.1007/s10620-024-08664-7

Field-Weighted Citation Impact: 3.10

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Fecal Immunochemical Test Positivity Thresholds: An International Survey of Population-Based Screening Programs

Authors

Abstract

Topics & Keywords

Publication Details