Repurposing Semaglutide and Liraglutide for Alcohol Use Disorder

202487 citationsJournal Articlehybrid Open Access

Authors

Markku Lähteenvuo · University of Eastern Finland

Jari Tiihonen · Niuvanniemi Hospital

Anssi Solismaa · Pirkanmaa Hospital District

Antti O. Tanskanen · Niuvanniemi Hospital

Ellenor Mittendorfer‐Rutz · Karolinska Institutet

Heidi Taipale · Stockholm County Council

Abstract

Among patients with AUD and comorbid obesity/type 2 diabetes, the use of semaglutide and liraglutide were associated with a substantially decreased risk of hospitalization due to AUD. This risk was lower than that of officially approved AUD medications. Semaglutide and liraglutide may be effective in the treatment of AUD, and clinical trials are urgently needed to confirm these findings.

Topics & Keywords

Diabetes Treatment and Management Pharmacology and Obesity Treatment Alcohol Consumption and Health Effects

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: JAMA Psychiatry

Volume 82, Issue 1, pp. 94-94

DOI: 10.1001/jamapsychiatry.2024.3599

Field-Weighted Citation Impact: 30.85