Human Genetic Evidence to Inform Clinical Development of IL-6 Signaling Inhibition for Abdominal Aortic Aneurysm

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Authors

Stephen Burgess · University of Cambridge

Héléne T. Cronjé · University of Cambridge

Dipender Gill · Sequoia Sciences (United States)

Abstract

Inhibition of IL-6 signaling is a promising strategy for treating AAA but not other types of aneurysmal disease. These findings serve to help inform clinical development of IL-6 signaling inhibition for AAA treatment.

Topics & Keywords

Aortic aneurysm repair treatments Aortic Disease and Treatment Approaches Infectious Aortic and Vascular Conditions

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Arteriosclerosis Thrombosis and Vascular Biology

Volume 45, Issue 2, pp. 323-331

DOI: 10.1161/atvbaha.124.321988

Field-Weighted Citation Impact: 1.25