Disparities in response to mRNA SARS-CoV-2 vaccines according to sex and age: A systematic review

202411 citationsReviewgold Open Access

Authors

María Consuelo Bachmann · Swiss Academy of Medical Sciences

Nejla Gültekin · Swiss Academy of Medical Sciences

Zeno Stanga · Swiss Academy of Medical Sciences

Jan Fehr · Centre for Global Health Research

Ismail I. Ülgür · Swiss Academy of Medical Sciences

Patricia Schlagenhauf · Centre for Global Health Research

Abstract

Our results suggests that tailored vaccination may achieve maximum effectiveness and better tolerability depending on age and sex. Currently study results are rarely stratified by age and sex and this is a deficit in clinical trial publications. More research is needed to elucidate the biological mechanisms underlying the variations in vaccine responses according to age and sex.

Topics & Keywords

SARS-CoV-2 and COVID-19 Research COVID-19 Impact on Reproduction Vaccine Coverage and Hesitancy

UN Sustainable Development Goals

Zero hunger

Publication Details

Published in: New Microbes and New Infections

Volume 63, pp. 101551-101551

DOI: 10.1016/j.nmni.2024.101551

Field-Weighted Citation Impact: 4.39