Effects of vagus nerve stimulation on daily function and quality of life in markedly treatment-resistant major depression: Findings from a one-year, randomized, sham-controlled trial

202417 citationsJournal Articlegold Open Access

Authors

A. John Rush · Duke-NUS Medical School

Charles R. Conway · Washington University in St. Louis

Scott T. Aaronson · Sheppard Pratt Health System

Mark S. George · Ralph H. Johnson VA Medical Center

Patricio Riva‐Posse · Emory University

David L. Dünner · Center for Anxiety and Depression

John Zajecka

Abstract

Active VNS was superior to sham VNS in improving QoL and psychosocial function in patients with TRD. VNS has a broader therapeutic impact than symptom improvement alone in patients with marked psychosocial impairment.

Topics & Keywords

Vagus Nerve Stimulation Research Treatment of Major Depression Neurological disorders and treatments

Publication Details

Published in: Brain stimulation

Volume 18, Issue 3, pp. 690-700

DOI: 10.1016/j.brs.2024.12.1187

Field-Weighted Citation Impact: 4.15

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Effects of vagus nerve stimulation on daily function and quality of life in markedly treatment-resistant major depression: Findings from a one-year, randomized, sham-controlled trial

Authors

Abstract

Topics & Keywords

Publication Details