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Purpose This study focuses on the complex dynamics of food supply chain safety, safety governance and security in Pakistan’s food industry. By delving into the connections between hygiene practices, safety governance, customer perceptions, supplier attitudes and food safety outcomes, this study aims to shed light on the elements that shape food safety governance in the region. Design/methodology/approach An analysis was conducted using self-administered questionnaires, with data collected from 352 individuals recruited from different departments within Pakistan’s food supply chain businesses. Using STATA software, we calculated important variables’ direct and indirect effects on the scales taken from previous studies by applying structural equation modeling (SEM) and path analysis. Findings The analysis found significant relationships between safety governance, hygiene practices, consumer perceptions, supplier attitudes and food safety outcomes. Violations of hygiene standards considerably impacted food safety and security; the relationship between these violations and food safety results was mediated by consumer psychological capital. Furthermore, the correlation between cleanliness procedures and food safety results was observed to be moderated by supplier attitudes. Research limitations/implications Even though the study has dramatically improved our understanding of food safety governance, we must acknowledge its limitations and consider future research. Researchers may expand knowledge in this critical area and promote evidence-based policies and practices to improve food safety and security by addressing these constraints and exploring new directions. Cooperation across disciplines and sectors can create a more robust, reliable and sustainable food system. This approach will protect public health and improve communities worldwide. Practical implications The results have practical implications, as analysis found significant relationships between safety governance, hygiene practices, consumer perceptions, supplier attitudes and food safety outcomes. Violations of hygiene standards considerably impacted food safety and security; the relationship between these violations and food safety results was mediated by consumer psychological capital. Furthermore, the correlation between cleanliness procedures and food safety results was observed to be moderated by supplier attitudes. Social implications For policymakers, regulatory agencies, industry stakeholders and consumers, the findings emphasize the importance of strict hygiene standards, consumer trust and engagement and supply chain partner collaboration to ensure food system safety and security. Originality/value This study illuminates the intricate interactions that shape food safety governance in Pakistan’s food supply chain business. For policymakers, regulatory agencies, industry stakeholders and consumers, the findings emphasize the importance of strict hygiene standards, consumer trust and engagement and supply chain partner collaboration to ensure food system safety and security.