Longitudinal FDG-PET Metabolic Change Along the Lewy Body Continuum

20259 citationsJournal Articlegreen Open Access

Authors

Daniel Ferreira · Mayo Clinic

Scott A. Przybelski · Mayo Clinic in Florida

Timothy G. Lesnick · Mayo Clinic in Florida

Patricia Diaz‐Galvan · Mayo Clinic

Christopher G. Schwarz · Mayo Clinic

Melissa M. Murray · Mayo Clinic in Florida

Dennis W. Dickson ·

Abstract

This study found that brain hypometabolism begins to evolve during the prodromal stages of DLB with changes paralleling symptomatic progression. These data may inform clinical practice and trials planning to use FDG-PET for biologic staging, monitoring disease progression, and potentially assessing treatment response.

Topics & Keywords

Dementia and Cognitive Impairment Research Alzheimer's disease research and treatments Parkinson's Disease Mechanisms and Treatments

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: JAMA Neurology

Volume 82, Issue 3, pp. 285-285

DOI: 10.1001/jamaneurol.2024.4643

Field-Weighted Citation Impact: 12.92