Cerebrospinal fluid dynamics and subarachnoid space occlusion following traumatic spinal cord injury in the pig: an investigation using magnetic resonance imaging

Spinal-level specific changes to CSF dynamics, with concurrent changes to SAS occlusion, occurred after SCI in the pig, suggesting that CSF pulsatility and craniospinal compliance were altered in the sub-acute post-traumatic period. These results suggest that PC-MRI derived CSF dynamics may provide a non-invasive method to investigate functional alterations to the spinal intrathecal space following traumatic SCI.