Can ChatGPT4-vision identify radiologic progression of multiple sclerosis on brain MRI?

Without fine-tuning or the need for prior coding experience, GPT4V can perform a zero-shot radiologic change detection task with reasonable accuracy. However, in absolute terms, in a simplified "spot the difference" medical imaging task, GPT4V was inferior to state-of-the-art computer vision methods. GPT4V's performance metrics were more similar to the ViT than the U-net. This is an exploratory experimental study and GPT4V is not intended for use as a medical device.