α-Synuclein Seed Amplification Assay Amplification Parameters and the Risk of Progression in Prodromal Parkinson Disease

202522 citationsJournal Articlehybrid Open Access

Authors

David G. Coughlin · University of California San Diego

Ben Shifflett · University of California San Diego

Carly M. Farris · Amprion (United States)

Yihua Ma · Amprion (United States)

Douglas Galasko · University of California San Diego

Steven D. Edland · University of California San Diego

Brit Mollenhauer

Abstract

αSyn-SAA positivity and faster seed amplification are associated with a greater risk of developing PD in at-risk individuals and may aid in predicting phenoconversion.

Topics & Keywords

Parkinson's Disease Mechanisms and Treatments Neurological disorders and treatments Botulinum Toxin and Related Neurological Disorders

Publication Details

Published in: Neurology

Volume 104, Issue 5, pp. e210279-e210279

DOI: 10.1212/wnl.0000000000210279

Field-Weighted Citation Impact: 29.69

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α-Synuclein Seed Amplification Assay Amplification Parameters and the Risk of Progression in Prodromal Parkinson Disease

Authors

Abstract

Topics & Keywords

Publication Details