Neutralizing and binding antibody dynamics following primary and booster COVID-19 vaccination among healthcare workers

20253 citationsJournal Articlegold Open Access

Authors

Irmak Güzel · Ministry of Health

Gamze ÖZTÜRK · Dokuz Eylül University

Özgür Appak · Dokuz Eylül University

Derya Çağlayan · Ministry of Health

Ahmet Furkan Süner · Tecumseh Products (United States)

Çağlar Irmak · Hakkari University

Neslişah Türe ·

Abstract

NAbs levels decreased rapidly after primary CoronaVac vaccination. Boosters significantly increased levels while the heterologous vaccine combination induced a greater response. Anti-RBD IgG levels were able to predict the NAb response, however the correlation varied by the vaccine type, NAb response strength and the time since vaccination.

Topics & Keywords

SARS-CoV-2 and COVID-19 Research COVID-19 Clinical Research Studies Vaccine Coverage and Hesitancy

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: BMC Infectious Diseases

Volume 25, Issue 1, pp. 218-218

DOI: 10.1186/s12879-025-10621-2

Field-Weighted Citation Impact: 4.10