Transcallosal white matter and cortical gray matter variations in autistic adults aged 30–73 years

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Authors

Young Seon Shin · University of Florida

Danielle Christensen · University of Florida

Jingying Wang · University of Florida

Desirae J. Shirley · University of Florida

Ann-Marie Orlando · University of Florida

Regilda A. Romero · University of Florida

David E. Vaillancourt ·

Abstract

Our findings revealed increased free water load in frontal white matter in autistic adults and identified distinct age-associated microstructural variations between the two groups. These findings highlight more heterogeneous brain aging profiles in autistic adults. Our study also demonstrated the importance of quantifying free water in dMRI studies of ASD.

Topics & Keywords

Autism Spectrum Disorder Research Genetics and Neurodevelopmental Disorders Genomic variations and chromosomal abnormalities

Publication Details

Published in: Molecular Autism

Volume 16, Issue 1, pp. 16-16

DOI: 10.1186/s13229-025-00652-6

Field-Weighted Citation Impact: 11.21

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Transcallosal white matter and cortical gray matter variations in autistic adults aged 30–73 years

Authors

Abstract

Topics & Keywords

Publication Details