Clinical practice guideline protocol for perioperative glycemic control in diabetic and nondiabetic adults undergoing noncardiac surgery

Abstract Introduction Type II diabetes mellitus (DM II) is a chronic and prevalent disease affecting millions of people worldwide, with a significant impact on public health. This protocol outlines the methodology for developing a Clinical Practice Guideline (CPG) focused on managing glycemic control in diabetic and nondiabetic adults undergoing noncardiac surgery. The objective of this guideline is to provide recommendations based on the best available evidence, improving the quality of care and clinical outcomes for these patients. Methods The CPG will be developed using the GRADE methodology, a rigorous and transparent approach that allows for the evaluation of evidence quality and the formulation of robust recommendations. The process will include identifying critical clinical questions using the PECOT format, ensuring a comprehensive evaluation of perioperative glycemic management. Questions The clinical questions addressed in this CPG cover key aspects of perioperative glycemic management, from defining preoperative hyperglycemia to strategies for intraoperative and postoperative monitoring. These questions were prioritized through a modified Delphi process, ensuring their clinical relevance.