Standardized Definition of Progression Independent of Relapse Activity (PIRA) in Relapsing-Remitting Multiple Sclerosis

202526 citationsJournal Articlegreen Open Access

Authors

Jannis Müller · The Royal Melbourne Hospital

Sifat Sharmin · The Royal Melbourne Hospital

Johannes Lorscheider · University of Basel

Serkan Özakbaş · İzmir University of Economics

Rana Karabudak · Yeditepe University Hospital

Dana Horáková · Charles University

Bianca Weinstock-Guttman

Abstract

Incidence and persistence of PIRA are determined by the definition used. The proposed standardized definition aims to enhance comparability among studies.

Topics & Keywords

Multiple Sclerosis Research Studies Polyomavirus and related diseases

UN Sustainable Development Goals

Reduced inequalities

Publication Details

Published in: JAMA Neurology

Volume 82, Issue 6, pp. 614-614

DOI: 10.1001/jamaneurol.2025.0495

Field-Weighted Citation Impact: 37.07