The efficacy of 5-aminolevulinic acid photodynamic therapy in inducing cell death in multidrug-resistant Trichophyton mentagrophytes: An in vivo and in vitro study

These findings suggest that ALA-PDT disrupts the cell membrane, cell wall and internal cellular structure of T. mentagrophytes through increasing the release of Reactive Oxygen Species (ROS), thereby facilitating the elimination of the fungus. This research highlights the therapeutic potential of ALA-PDT as an innovative strategy for managing fungal infections, particularly those resistant to conventional treatments.