Wheat germ agglutinin-nanoparticles encapsulating itacitinib target and suppress pro-inflammatory slan+ monocytes

20250 citationsJournal Article

Authors

Karen Valdés Álvarez · Universidad de Antioquia

Cristian Anacona · Universidad de Antioquia

Esneyder Ruiz Agudelo · Universidad de Antioquia

Paula X. Losada · Universidad de Antioquia

Víctor H. Orozco · Universidad de Antioquia

Luis F. Giraldo · Universidad de Antioquia

Gloría Vásquez ·

Abstract

ITA-loaded WGA/F127/PNPs effectively target and suppress pro-inflammatory slan+ monocytes, presenting a promising, cell-specific therapeutic approach for managing systemic lupus erythematosus and related autoimmune disorders.

Topics & Keywords

Systemic Lupus Erythematosus Research Immune Cell Function and Interaction T-cell and B-cell Immunology

UN Sustainable Development Goals

Zero hunger

Publication Details

Published in: Nanomedicine

Volume 20, Issue 10, pp. 1113-1126

DOI: 10.1080/17435889.2025.2494500

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