Measuring neurofilament light in human plasma and cerebrospinal fluid: a comparison of five analytical immunoassays

20251 citationsPreprintgreen Open Access

Authors

Udit Sheth · Jacksonville College

Rebecca Harrison · GW Pharmaceuticals (United Kingdom)

Kyle Ferber · Biogen (United States)

Erin G. Rosenbaugh · Foundation for the National Institutes of Health

Amanda Bevis · Foundation for the National Institutes of Health

Rohini Khillan · Foundation for the National Institutes of Health

Michael Benatar

Abstract

Four NfL assays demonstrated similar analytic performance. Alongside performance, other factors such as costs, accessibility, useability, footprint, and intended use, should be considered.

Topics & Keywords

Amyotrophic Lateral Sclerosis Research

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: bioRxiv (Cold Spring Harbor Laboratory)

DOI: 10.1101/2025.05.05.652212