Buzhong Yiqi decoction improves inflammation and oxidative damage in autoimmune thyroiditis by inhibiting apoptosis via the SIRT1-Mediated Nrf2/NF-κB axis

The findings from this study establish that BZYQ exhibits potent antioxidant and anti-inflammatory activities via the SIRT1-mediated Nrf2/NF-κB p65 axis, reducing thyroid cell apoptosis. These observations unveil a novel mechanism and support the potential of BZYQ as a promising therapeutic agent for AIT.