Cost-Effectiveness of α<sub>2</sub> Agonists for Intravenous Sedation in Patients With Critical Illness

20251 citationsJournal Articlegold Open Access

Authors

Stephen Morris · University of Cambridge

Nazir Lone · Clinical Trial Investigators

Cathrine McKenzie · NIHR Southampton Biomedical Research Centre

Christopher J. Weir · Clinical Trial Investigators

Timothy Walsh · Clinical Trial Investigators

A2B trial investigators · Clinical Trial Investigators

Natalie Pattison ·

Abstract

In this study, dexmedetomidine-, clonidine-, and propofol-based IV sedation in patients with critical illness receiving mechanical ventilation had similar costs and QALYs. These findings suggest that economic considerations should not affect which sedative these patients receive.

Topics & Keywords

Intensive Care Unit Cognitive Disorders Anesthesia and Sedative Agents Cardiac, Anesthesia and Surgical Outcomes

Publication Details

Published in: JAMA Network Open

Volume 8, Issue 5, pp. e2517533-e2517533

DOI: 10.1001/jamanetworkopen.2025.17533

Field-Weighted Citation Impact: 1.59

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Cost-Effectiveness of α<sub>2</sub> Agonists for Intravenous Sedation in Patients With Critical Illness

Authors

Abstract

Topics & Keywords

Publication Details