Exploring the association between vitamin D status and Corona Virus-19 infection in a cohort of adults aged 50 years and older

s u m m a r yObjective: Evaluate the association between vitamin D (vitD) status and Corona infection in adults aged 50 years and older.Design: Adults 50 undergoing COVID-19 testing from July 2020 to December 2021, without prior vaccination, consented to blood analysis.SARS-CoV-2 PCR confirmed current COVID-19 infection.VitD status was assessed via 25(OH)D concentration (LCMS/MS, ZRT Labs, Portland, OR).Sociodemographic data were collected at enrollment.Statistical analyses (SAS 9.4) examined associations between sociodemographics, COVID-19, and vitD status.Multivariate logistic regression analyzed factors linked to COVID-19 or vitD status.Results: Of 131 participants, 46.6% were 65 years old, 71.0% married, 19.9% Black American, 36.6% male, 38.9% Medicaid/