Ferroximend Improves Nonvascularized Bone Graft Incorporation in the Irradiated Rat Mandible

20250 citationsJournal Article

Authors

Keshav B. Lalchandani · University of Michigan–Ann Arbor

Alexis Donneys · University of Michigan–Ann Arbor

Noah S. Nelson · University of Michigan–Ann Arbor

Melissa Daniel · University of Michigan–Ann Arbor

Kevin M. Urlaub · University of Michigan–Ann Arbor

Jeremy V. Lynn · University of Michigan–Ann Arbor

Kyle Cragg

Abstract

Our results suggest that the implantation of Ferroximend during NVBG reconstruction can remediate the damaging effects of radiotherapy. Upon clinical translation, countless patients may benefit from the successful reintroduction of nonvascularized bone grafting as a reconstructive option in oncologic reconstruction after radiotherapy.

Topics & Keywords

Bone health and treatments Boron Compounds in Chemistry Dental Implant Techniques and Outcomes

Publication Details

Published in: Annals of Plastic Surgery

Volume 95, Issue 1, pp. 93-99

DOI: 10.1097/sap.0000000000004355

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Ferroximend Improves Nonvascularized Bone Graft Incorporation in the Irradiated Rat Mandible

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Abstract

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Publication Details