Proteolytic stabilization of a spider venom peptide results in an orally active bioinsecticide

20251 citationsJournal Articlehybrid Open Access

Authors

Barry R. Davis · Vestaron (United States)

Alexandra Haase · Vestaron (United States)

Joseph S. Tourtois · Vestaron (United States)

Daniel Hulbert · Vestaron (United States)

Rosemary B. Cornell · Vestaron (United States)

Brian T. DeVree · Vestaron (United States)

Cadence J. Flohrschutz

Abstract

A novel, peptide-based bioinsecticide derived from spider venom was developed to be stable and active by ingestion by lepidopteran pests. The peptide, U1-AGTX-Ta1b-QA, can replace or reduce the use of chemical insecticides and has been approved by the United States Environmental Protection Agency. © 2025 The Author(s). Pest Management Science published by John Wiley & Sons Ltd on behalf of Society of Chemical Industry.

Topics & Keywords

Insect Resistance and Genetics Insect and Pesticide Research Entomopathogenic Microorganisms in Pest Control

Publication Details

Published in: Pest Management Science

Volume 81, Issue 10, pp. 6404-6415

DOI: 10.1002/ps.8980

Field-Weighted Citation Impact: 0.81

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Proteolytic stabilization of a spider venom peptide results in an orally active bioinsecticide

Authors

Abstract

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Publication Details