Lessons learned from aldehyde dehydrogenases as non-P450 aldehyde-oxidizing enzymes: implications for the ‘exposome’ and human health

Integrating ALDH biology into exposome research offers a powerful path toward precision risk assessment and possible interventions. Given their public health and clinical relevance, future efforts should prioritize mapping ALDH-exposome interactions, genetic screening, and developing ALDH-targeted interventions.