Stereotactic Radiosurgery in Patients With Small Cell Lung Cancer and 1-10 Brain Metastases: A Multi-Institutional, Phase II, Prospective Clinical Trial

202511 citationsJournal Article

Authors

Ayal A. Aizer · Brigham and Women's Hospital

Shyam Tanguturi · Brigham and Women's Hospital

Diana D. Shi · Brigham and Women's Hospital

Paul J. Catalano · Dana-Farber Cancer Institute

Kee‐Young Shin · Dana-Farber Cancer Institute

Ivy Ricca · Brigham and Women's Hospital

Marciana Johnson

Abstract

Our prospective, multi-institutional study demonstrated low rates of neurologic death when SRS/SRT as opposed to WBRT is used in patients with SCLC and 1-10 brain metastases who are surveilled closely post-treatment, supporting the utility of stereotactic approaches in this population.

Topics & Keywords

Brain Metastases and Treatment Lung Cancer Research Studies Glioma Diagnosis and Treatment

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Journal of Clinical Oncology

Volume 43, Issue 27, pp. 2986-2997

DOI: 10.1200/jco-25-00056

Field-Weighted Citation Impact: 16.72