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The MENA region faces substantial water scarcity and quality challenges, intensified by limited freshwater resources and extensive pollution. In Egypt and Lebanon, these issues are particularly severe due to reliance on compromised water sources. Egypt depends heavily on the Nile River, which suffers from pollution and overuse, while Lebanon contends with widespread water quality issues stemming from contamination and aging infrastructure. Addressing the growing demand for clean water in these areas involves a range of treatment methods, from coagulation to advanced desalination technologies. Among these, reverse osmosis (RO) has emerged as a crucial solution for freshwater production in arid regions such as the Middle East, where traditional water sources are insufficient. This study presents a case involving a solar-powered RO unit with a capacity of 10 cubic meters, installed in Abo El-Nersh village, Monufia Governorate, Egypt. The unit, powered entirely by solar energy, represents a sustainable model for water purification and resource management. The study also explores an innovative approach to utilizing the brine, or reject water, generated by the RO process. Typically considered a waste product, this brine water is repurposed in this project for aquaculture, specifically for breeding fish that thrive in low-salinity conditions. This dual-purpose use of brine not only reduces waste but also supports local food production by enabling sustainable fish farming. By combining RO technology, renewable energy, and aquaculture, this model demonstrates a holistic approach to addressing water scarcity and improving food security in the MENA region. The findings suggest that with strategic use of solar-powered RO and brine recycling for fish breeding, countries in the region can make strides in water management, resource optimization, and sustainable agriculture, thus supporting both environmental and socio-economic goals.