XBB.1.5 COVID-19 mRNA Vaccines Induce Inadequate Mucosal Immunity in Patients with Inflammatory Bowel Disease

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Authors

Simon Woelfel · University of St.Gallen

Joel Dütschler · University of St.Gallen

Daniel Junker · Natural and Medical Sciences Institute

Marius König · University of St.Gallen

Georg Leinenkugel · University Hospital of Basel

Claudia Krieger‐Grübel · University of St.Gallen

Samuel Truniger

Abstract

Since mucosal IgA plays a pivotal role in infection control, the lack of IgA induction indicates that patients lack sufficient protection against SARS-CoV-2 infections which warrants the development of mucosal COVID-19 vaccines.

Topics & Keywords

SARS-CoV-2 and COVID-19 Research Immunotherapy and Immune Responses T-cell and B-cell Immunology

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Vaccines

Volume 13, Issue 7, pp. 759-759

DOI: 10.3390/vaccines13070759

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