Abnormalities of thalamus and thalamocortical pathways in patients with refractory epilepsy caused by focal cortical dysplasia – <scp>MRI</scp> study

This study used advanced MRI techniques to examine the thalamus - a deep brain structure that relays signals and helps coordinate brain activity - in people with focal epilepsy caused by abnormal development of the cerebral cortex, the part of the brain responsible for thinking, movement, and sensory processing, and where seizures often begin. Researchers found subtle structural changes in the thalamus and its connections to the cortex, even beyond the area directly affected by the lesion. These results provide new insight into how epilepsy can disrupt brain networks and offer a foundation for future studies using modern neuroimaging techniques.