PSA Secretion from Single Circulating Tumor Cells of Metastatic Castration-Naïve Prostate Cancer Patients

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Authors

Eshwari Dathathri · University of Twente

Fikri Abali · University of Twente

Michiel Stevens · Novay

Richell Booijink · University of Twente

Tanja C. van Dijk · Erasmus MC Cancer Institute

Khrystany T. Isebia · Erasmus MC Cancer Institute

John W.M. Martens ·

Abstract

This study reveals heterogeneity in PSA secretion among individual CTCs from patients with mCNPC prior to any therapeutic intervention, thereby highlighting the limitations of PSA as a biomarker.

Topics & Keywords

Prostate Cancer Treatment and Research Cancer Cells and Metastasis Immunotherapy and Immune Responses

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Cancer Research Communications

Volume 5, Issue 8, pp. 1359-1371

DOI: 10.1158/2767-9764.crc-25-0158

Field-Weighted Citation Impact: 1.52