Trends in Fomepizole Use for Acetaminophen Poisoning in the United States; 2013–2024

20253 citationsJournal Articlehybrid Open Access

Authors

Mitchell D'Aloia · University of Chicago Medical Center

Dale L. Smith · University of Illinois Chicago

Randy A. Boley · University of Illinois Chicago

Emily Schamber · University of Illinois Chicago

Dillon Thorpe · University of Illinois Chicago

Trevonne M. Thompson · Molecular Biology Consortium

Neeraj Chhabra

Abstract

Fomepizole use in acetaminophen poisoning has risen dramatically since 2019, particularly among patients at highest risk for death and liver transplantation. It is of critical importance to determine the efficacy of fomepizole for acetaminophen poisoning.

Topics & Keywords

Drug-Induced Hepatotoxicity and Protection Poisoning and overdose treatments Pharmacogenetics and Drug Metabolism

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Journal of Medical Toxicology

Volume 21, Issue 4, pp. 404-408

DOI: 10.1007/s13181-025-01091-8

Field-Weighted Citation Impact: 4.90