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Periods of heat lead to increased mortality and morbidity. The aim of the present study was to investigate whether a trend of rescue deployments on heat days (Tmax≥32°C) from 2014 to 2024 is recognizable, whether morbidity already increases at lower temperatures (Tmax≥30°C or≥28°C) and whether an exposure-response curve is recognizable - for all patients and separately for different age groups.All 250,507 deployments from June to August 2014-2024 in Frankfurt am Main and weather data from the German meteorological Service at the Frankfurt weather station were used for the study. For each year, the deployments on heat days were compared with those on non-heat days (difference and ratio). Using the pairs of values (year, additional number of rescue missions on heat days with Tmax≥32°C), a linear regression model was adapted for the years 2014 to 2024 and the trend in the additional number of missions per year was estimated. Additional analyses were carried out for Tmax≥30°C and≥28°C. For the calculation of the exposure-response curve, the exposures over all years were calculated according to daily Tmax in 2°C steps, with Tmax<18°C as reference. These analyses were carried out for all patients and for age groups up to 59 years, 60-79 years and 80 years and older.Between 2014 and 2024, the additional deployments on heat days with Tmax≥32°C decreased significantly from+25 in 2014 to - 6.6 in 2024 (- 2.9; 95% CI - 3.5 - - 2.4). Overall, 6.2% (ratio=1.062 (95% CI: 1.050-1.075)) more deployments were required on heat days with Tmax≥32°C than on days without this definition, comparable to days with Tmax≥30°C (+6.3%; ratio=1.063 (95% CI: 1.053-1.073)), or≥28°C (+6.1%; ratio=1.061 (95% CI: 1.052-1.069)). The largest increase was seen in patients under 60 years of age, The dose-response curve showed a linear increase of 27% in those under 60 and 16% in those over 80, with the latter reaching a plateau at Tmax 28°C and above.The decreasing additional need for deployments at Tmax≥32°C could indicate an adaptation of the population, but requires further investigation. Morbidity already increases on days with lower Tmax. As people≤60 y are particularly affected, prevention measures should be strengthened and extended to younger, working people.