Identification of the prognostic effect of mitophagy-related genes in acute myeloid leukemia

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Authors

Xuan Fan · Hebei Medical University

Wenyuan Zhu · Hebei Medical University

Baoxi Zhang · Second Hospital of Hebei Medical University

Haichao Zhao · Second Hospital of Hebei Medical University

Chaonan Li · Second Hospital of Hebei Medical University

Xiaoyun Wu · Second Hospital of Hebei Medical University

Abstract

This study identified five mitophagy-related genes as prognostic biomarkers in AML and developed a robust risk model that correlates with survival outcome, immune infiltration, and drug sensitivity. These findings offer new insights into mitophagy-related mechanisms in AML and may guide personalized therapeutic strategies.

Topics & Keywords

Acute Myeloid Leukemia Research Histone Deacetylase Inhibitors Research Autophagy in Disease and Therapy

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Frontiers in Immunology

Volume 16, pp. 1580597-1580597

DOI: 10.3389/fimmu.2025.1580597

Field-Weighted Citation Impact: 3.72

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