Global prevalence of nitrofurantoin-resistant uropathogenic <i>Escherichia coli</i> (UPEC) in humans: a systematic review and meta-analysis

The findings show considerable global prevalence of nitrofurantoin-resistant UPEC isolates, with the prevalence being higher in low- and middle-income countries (LMICs). Sufficient education should be provided where possible, and antimicrobial stewardship should be intensified to slow the rate of AMR increase worldwide.