Ein mann i 30-åra med psykose og nøytropeni

Patients with Asperger's syndrome and epilepsy are at higher risk of psychosis. On admission, the patient's delusions improved with increased olanzapine dosage, after which the medication was discontinued due to severe neutropenia. Discontinuation of olanzapine and supplementary vitamin injections did not improve the blood count. Further investigations raised suspicion of a primary bone marrow disorder. After further investigation, including a bone marrow examination, acute lymphoblastic leukaemia (ALL) was diagnosed. The case highlights the importance of thoroughly investigating serious haematologic abnormalities. It also raises questions about the potential role of long-term antiepileptic medication exposure in the development of leukaemia, which warrants further research.