Efficacy and Safety of a Novel Triple Single-Pill for Uncontrolled Hypertension

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Authors

Vagner Madrini · Hospital Israelita Albert Einstein

Caio A.M. Tavares

Mônica Camelo Pessoa de Azevedo Albuquerque · Hospital Israelita Albert Einstein

Odílson Marcos Silvestre · Universidade Federal do Acre

João Soares Felício · Universidade Federal do Pará

Fábio Serra Silveira · Hospital do Coração

Miguel Nasser Hissa · Diabetes Australia

Abstract

In patients with uncontrolled hypertension, a novel triple single-pill containing candesartan cilexetil, amlodipine, and chlorthalidone improved BP control at 12 weeks and had a reasonable safety profile. (Candesartan Cilexetil + Chlorthalidone + Amlodipine Versus Exforge HCT for Systemic Arterial Hypertension [OPTION TREAT]; NCT05920005).

Topics & Keywords

Blood Pressure and Hypertension Studies

Publication Details

Published in: JACC Advances

Volume 4, Issue 10, pp. 102175-102175

DOI: 10.1016/j.jacadv.2025.102175

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Efficacy and Safety of a Novel Triple Single-Pill for Uncontrolled Hypertension

Authors

Abstract

Topics & Keywords

Publication Details