Directed-Complement Activation as a Novel Immunotherapeutic Approach for HER2-Breast Cancer

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Authors

Carole Seguin‐Devaux · Luxembourg Institute of Health

Bianca Brandus · Luxembourg Institute of Health

Jean‐Marc Plesséria · Luxembourg Institute of Health

Gilles Iserentant · Luxembourg Institute of Health

Jean-Yves Servais · Luxembourg Institute of Health

Aubin Pitiot · Luxembourg Institute of Health

Georgia Kanli

Abstract

We showed here that directed complement activation on tumor cells is an alternative to therapeutic antibodies for future combination therapies upon resistance to standard-of-care treatment.

Topics & Keywords

Monoclonal and Polyclonal Antibodies Research Glycosylation and Glycoproteins Research Immunotherapy and Immune Responses

Publication Details

Published in: ImmunoTargets and Therapy

Volume Volume 14, pp. 979-995

DOI: 10.2147/itt.s517584

Field-Weighted Citation Impact: 2.92

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Directed-Complement Activation as a Novel Immunotherapeutic Approach for HER2-Breast Cancer

Authors

Abstract

Topics & Keywords

Publication Details