Clinical Experience-Based Chronicle of the Use of Colloidal Nano Silver in Indian Patients with Wounds: A Multicentre Surveillance Study

Background: Topical silver therapies and silver-based dressings are being used more frequently for localized wound care; however, the supporting evidence for their effectiveness remains unclear. Therefore, this study aimed to capture the clinical use, outcomes, and perceptions of healthcare professionals (HCPs) regarding colloidal nano silver in Indian patients with wounds. Methods: This questionnaire-based study was designed to assess the use of colloidal nano silver in wounds within the Indian real-world settings. A questionnaire comprising 18 questions focusing on wound etiology, wound size, prior treatment history, clinical response to colloidal silver gel, pathogen identification, and treatment outcomes. Results: A total 87 HCPs were enrolled in the study. According to 72.41% of HCPs, diabetic foot ulcer (DFU) was the most common etiology of wounds in patients treated with colloidal silver gel. About 54% of HCPs reported that >3 out of 10 patients had been previously treated with topical mupirocin dressings but had failed to heal. According to 55.17% of HCPs, >7 out of 10 patients treated with colloidal silver gel showed a 50% reduction in ulcer size by day 14. The majority of HCPs (33.33%) reported that 5 out of 10 patients treated with colloidal silver gel showed complete ulcer healing. About 67% of HCPs reported that patients with DFU had complete wound healing. Staphylococcus aureus (41.38%) was the most reported pathogens identified in patients with DFU. Conclusion: This study demonstrates that colloidal nano silver gel is a safe, effective, and well-tolerated option for wound care, promoting faster healing and strong antimicrobial activity, especially in DFU. Key words: Colloidal nano silver, wound healing, diabetic foot ulcer, healthcare professionals