Development of a functional sarcopenia model utilizing a microcantilever microphysiological system as a phenotypic disease model

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Authors

Himanshi Jangir · University of Central Florida

Leandro Gallo · University of Central Florida

Russell Emmons · Hesperos (United States)

James J. Hickman · University of Central Florida

Abstract

Development of the first defined in vitro functional model of sarcopenia on a microcantilever platform. This study recapitulates physiological signatures of disease progression characterized by loss of muscle mass and function and an increase in reactive oxygen species.

Topics & Keywords

Muscle activation and electromyography studies Spaceflight effects on biology Muscle Physiology and Disorders

Publication Details

Published in: In vitro models

Volume 5, Issue 1, pp. 63-78

DOI: 10.1007/s44164-025-00092-9

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Development of a functional sarcopenia model utilizing a microcantilever microphysiological system as a phenotypic disease model

Authors

Abstract

Topics & Keywords

Publication Details