Non‐Response to Obeticholic Acid Is Associated With Heightened Risks of Developing Clinical Events in Primary Biliary Cholangitis

20253 citationsJournal Articlehybrid Open Access

Authors

Nadir Abbas · Queen Elizabeth Hospital Birmingham

Rachel A. Smith · University of Cambridge

Ellina Lytvyak · University of Alberta

Miki Scraravaglio · University of Milano-Bicocca

Neil Halliday · Royal Free London NHS Foundation Trust

Amal Almahroos · Queen Elizabeth Hospital Birmingham

Nadia Eden

Abstract

Biochemical response stratifies risk of clinical events in PBC patients under OCA treatment. Whilst response rates increase over time, discontinuation rates underscore the need for newer treatment paradigms.

Topics & Keywords

Liver Diseases and Immunity Gallbladder and Bile Duct Disorders Pediatric Hepatobiliary Diseases and Treatments

Publication Details

Published in: Alimentary Pharmacology & Therapeutics

Volume 63, Issue 4, pp. 494-506

DOI: 10.1111/apt.70378

Field-Weighted Citation Impact: 4.02

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Non‐Response to Obeticholic Acid Is Associated With Heightened Risks of Developing Clinical Events in Primary Biliary Cholangitis

Authors

Abstract

Topics & Keywords

Publication Details