Immunotherapy against colorectal cancer via delivery of anti-PD-L1 nanobody mRNA

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Authors

Wen-Ming Chu · University of Hawaiʻi at Mānoa

Li Ma · University of Hawaiʻi at Mānoa

Brian E. Hew · University of Hawaiʻi at Mānoa

Atsushi Sugawara · University of Hawaiʻi at Mānoa

Rodrigo Wengrill · University of Hawaiʻi at Mānoa

Alex Guarary · University of Hawaiʻi at Mānoa

Jason Irei

Abstract

These results suggest that the PDL1Nb therapy is effective for both CAC and sCRC and using qPDL1Nb mRNA-LNP is a promising alternative strategy for CRC immunotherapy.

Topics & Keywords

Immunotherapy and Immune Responses Cancer Immunotherapy and Biomarkers Monoclonal and Polyclonal Antibodies Research

Publication Details

Published in: eGastroenterology

Volume 3, Issue 3, pp. e100106-e100106

DOI: 10.1136/egastro-2024-100106

Field-Weighted Citation Impact: 0.82

Command Palette

Immunotherapy against colorectal cancer via delivery of anti-PD-L1 nanobody mRNA

Authors

Abstract

Topics & Keywords

Publication Details