Quantitative EEG Biomarkers in the Genetic Epilepsies and Associations With Neurologic Outcomes

20255 citationsJournal Article

Authors

Peter D. Galer · Children's Hospital of Philadelphia

Jillian L. McKee · Children's Hospital of Philadelphia

Sarah M. Ruggiero · Children's Hospital of Philadelphia

Michael C. Kaufman · Children's Hospital of Philadelphia

William K.S. Ojemann · ATLAS Neuroengineering (Belgium)

Ian McSalley · Children's Hospital of Philadelphia

Shiva Ganesan

Abstract

These results suggest that some genetic epilepsies and functional outcome measures have distinct quantitative EEG signatures. Furthermore, EEG spectral features are predictive of some functional outcome measures. Large-scale retrospective quantitative analysis of clinical EEGs has the potential to discover novel biomarkers and to quantify and track individuals' disease progression across development.

Topics & Keywords

Diet and metabolism studies Mitochondrial Function and Pathology

Publication Details

Published in: Neurology

Volume 105, Issue 8, pp. e214148-e214148

DOI: 10.1212/wnl.0000000000214148

Field-Weighted Citation Impact: 5.83

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Quantitative EEG Biomarkers in the Genetic Epilepsies and Associations With Neurologic Outcomes

Authors

Abstract

Topics & Keywords

Publication Details