Use of real-world data and real-world evidence in NICE (UK) health technology appraisals of new therapeutics in oncology: a systematic review

This study quantifies the increasing use of diverse RWD sources in NICE oncology TAs, as well as the shift towards more complex methods like MAICs and ECAs. The feedback of the NICE committee highlights key areas of improvement as the generalisability and maturity of the RWD presented.