Role of Glyoxalase in Astrocytes’ Supportive Function Under Hyperglycemic Conditions: Aminoguanidine and Kir4.1 Channel Recovery

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Authors

Jadier Colón‐Vázquez · Central University of the Caribbean

Nathaly M. Rosado-Rivera · Universidad Complutense de Madrid

Joshua J. Navedo-Jackson · Central University of the Caribbean

Arelys A. Angueira-Laureano · University of Puerto Rico, Medical Sciences Campus

Yanitza Hernandez-Santiago · Central University of the Caribbean

Gerónimo Maldonado-Martínez · University of Puerto Rico System

Abstract

We demonstrated that regulation of the glyoxalase system via AG or another scavenger of carbonyl and aldehydes containing polyamine groups can contribute to the recovery of astrocyte function in diabetic patients.

Topics & Keywords

Biochemical effects in animals Advanced Glycation End Products research Nerve injury and regeneration

Publication Details

Published in: Brain Sciences

Volume 15, Issue 10, pp. 1075-1075

DOI: 10.3390/brainsci15101075

Field-Weighted Citation Impact: 1.19

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Role of Glyoxalase in Astrocytes’ Supportive Function Under Hyperglycemic Conditions: Aminoguanidine and Kir4.1 Channel Recovery

Authors

Abstract

Topics & Keywords

Publication Details