Protective efficacy of the UniFluVec influenza vaccine vector against the highly pathogenic influenza A/Indonesia/5/2005 (H5N1) strain in ferrets

20252 citationsJournal Articlehybrid Open Access

Authors

Julia Romanova · Orano (United States)

Artem Krokhin · Capricorn Automotive (United Kingdom)

Boris Ferko · Harmonic Drive (Germany)

Dirk Pleimes · Silence Therapeutics (Germany)

E Varečková · Institute of Virology of the Slovak Academy of Sciences

F Kostolanský · Institute of Virology of the Slovak Academy of Sciences

Andrej Egorov

Abstract

The replication-deficient UniFluVec vector demonstrates safety, immunogenicity, and protective efficacy against the heterologous HPAIV strain in ferrets following a single intranasal administration.

Topics & Keywords

Influenza Virus Research Studies SARS-CoV-2 and COVID-19 Research vaccines and immunoinformatics approaches

Publication Details

Published in: Vaccine

Volume 65, pp. 127795-127795

DOI: 10.1016/j.vaccine.2025.127795

Field-Weighted Citation Impact: 3.07

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Protective efficacy of the UniFluVec influenza vaccine vector against the highly pathogenic influenza A/Indonesia/5/2005 (H5N1) strain in ferrets

Authors

Abstract

Topics & Keywords

Publication Details