Predicting neurobehavioral outcomes in people with HIV

These findings have implications for HIV care by identifying PWH at risk for future adverse trajectories. The results may lead to insights informing future personalized interventions targeted to vulnerable subpopulations of PWH. Participants were enrolled in an earlier ART era with frequent prior AIDS and lower ART uptake and viral suppression than current practice; although subgroup analyses among virally suppressed PWH showed similar directions of effect, generalizability to consistently treated contemporary cohorts may be limited and requires confirmation in modern samples.