Preconditioning donors with corticosteroids improves early lung graft immunity

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Authors

Isabelle Schwartz-Cornil · Université de Versailles Saint-Quentin-en-Yvelines

Florentina Pascale · Université de Versailles Saint-Quentin-en-Yvelines

Luc Jouneau · Université de Versailles Saint-Quentin-en-Yvelines

Maxime Huriet · Université de Versailles Saint-Quentin-en-Yvelines

Jérôme Estephan · Université de Versailles Saint-Quentin-en-Yvelines

Mickaël Bourge · Centre National de la Recherche Scientifique

Abstract

Our results show that the early immune status of lung grafts is improved by treating donors with corticosteroids through macrophage-targeted mechanisms. This finding provides an immunological rationale for expanding the implementation of donor preconditioning with corticosteroids.

Topics & Keywords

Organ Transplantation Techniques and Outcomes Transplantation: Methods and Outcomes Clinical Nutrition and Gastroenterology

Publication Details

Published in: Frontiers in Immunology

Volume 16, pp. 1668591-1668591

DOI: 10.3389/fimmu.2025.1668591

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Preconditioning donors with corticosteroids improves early lung graft immunity

Authors

Abstract

Topics & Keywords

Publication Details