Label-free optical detection of miRNA using electrostatic interactions between oppositely charged gold nanoparticles for signal amplification

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Authors

Fatemeh Hakimian · University of Tehran

Behdad Delavari · UNSW Sydney

Samaneh Hadian-Ghazvini · University of Tehran

Mohammad Behnam Rad · University of Tehran

Fariba Dashtestani · University of Tehran

Vahid Sheikhhassani · Leiden University Medical Center

Hamideh Fouladiha ·

Abstract

In this study, we present a novel label-free optical biosensing mechanism for detecting miR-155, based on electrostatic interactions between oppositely charged gold nanoparticles.

Topics & Keywords

Advanced biosensing and bioanalysis techniques Gold and Silver Nanoparticles Synthesis and Applications RNA Interference and Gene Delivery

Publication Details

Published in: Sensors & Diagnostics

Volume 5, Issue 1, pp. 56-62

DOI: 10.1039/d5sd00129c

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Label-free optical detection of miRNA using electrostatic interactions between oppositely charged gold nanoparticles for signal amplification

Authors

Abstract

Topics & Keywords

Publication Details