Effect of dose interval of periosteal and intraarticular electrical dry needling boosters on pain and disability in patients with knee osteoarthritis: a multi-center randomized clinical trial

PIEDN boosters every 4 weeks were a more effective dosage regimen for maintaining improvements in pain, stiffness, function, and disability than once every 8 weeks or no further treatment sessions.Trial Registration: www.clinicaltrials.gov NCT05365061 May 4, 2022.