Sex differences in Alzheimer’s disease CSF biomarkers and their association with Aβ pathology on PET in cognitively unimpaired individuals

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Authors

Marta Milà‐Alomà · University of California, San Francisco

Carol Van Hulle · University of Wisconsin–Madison

Anna Brugulat‐Serrat · Pasqual Maragall Foundation

Margot Casals Brodú · Universitat Pompeu Fabra

Armand González‐Escalante · Pasqual Maragall Foundation

Gonzalo Sánchez‐Benavides · Pasqual Maragall Foundation

Mahnaz Shekari

Abstract

Our results suggest that tailoring core AD CSF biomarkers by sex is not necessary for detecting Aβ PET positivity in CU individuals. However, sex differences in their association with Aβ deposition could influence their prognostic or monitoring applications.

Topics & Keywords

Dementia and Cognitive Impairment Research Medical Imaging Techniques and Applications Neuroscience and Neuropharmacology Research

Publication Details

Published in: Alzheimer s Research & Therapy

Volume 17, Issue 1, pp. 235-235

DOI: 10.1186/s13195-025-01844-1

Field-Weighted Citation Impact: 4.52

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Sex differences in Alzheimer’s disease CSF biomarkers and their association with Aβ pathology on PET in cognitively unimpaired individuals

Authors

Abstract

Topics & Keywords

Publication Details